Nifoxipam is a novel depressant substance of the benzodiazepine class. Now produce at TGC-RC (The Grateful Chemicals) lab for educational and research purpose only.

Nifoxipam has potential use for the short-term treatment of anxiety, insomnia, acute seizures, and the sedation of hospitalized patients. However, it is currently exclusively sold by online research chemical vendors for use as a recreational psychoactive substance.

Subjective effects include anxiety suppression, disinhibition, anticonvulsant, hypnotic, muscle relaxing, and amnesia. The effects of nifoxipam are notably long-lived, although reported to be relatively subtle.

It is worth noting that the sudden discontinuation of benzodiazepines can be potentially dangerous or life-threatening for individuals using regularly for extended periods of time, sometimes resulting in seizures or death. It is highly recommended to taper one's dose by gradually lowering the amount taken each day for a prolonged period of time instead of stopping abruptly.

As with other benzodiazepines, nifoxipam has abuse potential and produces dependence with prolonged use. Additionally, very little data exists about its metabolism, pharmacology, and toxicity. It is highly advised to use harm reduction practices if using this substance.