Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug which is derived from the benzodiazepine family, and was invented in 1988. It is most closely related in structure to the GABA antagonist flumazenil, although its effects are somewhat different. It is classified as a high-potency benzodiazepine due to its high affinity binding to benzodiazepine binding sites where it acts as a partial agonist.Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome

This product is intended for laboratory research purposes only and are not to be used for any other purposes.

The effects are anxiolytic and sedating and its quite repulsive for most people. It can be hypnotic but not amnestic and dreams can get really crazy.

Effects are of course not nearly as intoxicating as things like clonazolam, but more pronounced than with pagoclone.

- We do not ship this product to Australia.